The Mitochondrial Stack & nanoNAD+™
Dr. Fenton LeBon's curated ecosystem for rebuilding human cellular bioenergetics. Featuring patent-pending nanoNAD+™ formulations, inner-membrane sealing peptides (SS-31), mitochondrial cleaners (MOTS-c), and top-grade qualified cellular supplements.
Crossing the Blood-Brain Barrier & Rebuilding the Krebs Cycle
Why single-molecule nanoNAD+ and targeted peptides succeed where standard oral supplements fail.
Rapid Blood-Brain Barrier Entry
At 1.92 nm, nanoNAD+ (especially intranasal and systemic solutions) rapidly bypasses peripheral vascular barriers. In TBI and PTSD, neurons suffer acute mitochondrial ATP starvation and hyperactive amygdala excitability. nanoNAD+ metabolized to adenosine binds A1 inhibitory receptors, suppressing excess glutamate and calming fear hyperarousal while replenishing ATP.
Plugging the Holes with SS-31
When mitochondrial inner membranes suffer oxidative trauma, cardiolipin peroxidation causes the cristae to leak protons. SS-31 (Elamipretide) selectively binds cardiolipin, physically sealing the microscopic “holes in the refinery” so the electrochemical proton gradient can spin the ATP synthase turbine at full power.
Tagging Broken Cells with MOTS-c
You cannot rebuild energy in a cell cluttered with dying organelles. MOTS-c activates mitochondrial quality control pathways, signaling the autophagic tagging and lysosomal destruction (mitophagy) of damaged mitochondria, clearing cellular real estate so Urolithin A and PGC-1α can replicate vibrant new ones.
nanoNAD+™ Dermal Solution
Source: Molecular World Health
The world's first single-molecule (1.92 nm) topical NAD+ solution. Declumped via patent-pending nanotechnology for deep dermal pore penetration.
Penetrates stratum corneum pores to fuel senescent dermal fibroblasts, activate SIRT3-SOD2 antioxidant defense, and stimulate collagen synthesis.
Target: Dermal Fibroblasts • SIRT1 • SOD2
Protocol: Apply 4–6 drops morning and evening to cleansed face, neck, or localized areas.
Retail Price$195.00
Order Direct via Official StorenanoNAD+ 10% + GHK-Cu 0.5% Combo Cream (30g)
Source: PrecisionPharma FL
High-potency synergy combining 3,000mg nanoNAD+ with 150mg GHK-Cu copper peptide in an airless pump jar for skin remodeling and mitochondrial recovery.
Synergizes bioenergetic NAD+ substrate with copper tripeptide gene remodeling, stimulating collagen synthesis while quenching reactive oxygen species.
Target: Dermal Extracellular Matrix • Fibroblasts • SIRT1
Protocol: Pea-sized amount to face/neck 1–2× daily. Refrigerate at 2–8 °C.
Retail Price$275.00
Prescribe via PrecisionPharmananoNAD+™ Concentrated Nasal Spray (15mL × 300mg/mL)
Source: PrecisionPharma FL
Fast-acting intranasal nano-formulation engineered to bypass systemic metabolism and cross the cribriform plate directly into the central nervous system.
Crosses the blood-brain barrier rapidly to fuel neuronal ATP synthesis, activate SARM1 axonal maintenance, and stimulate adenosine A1 inhibitory calming pathways for TBI & PTSD recovery.
Target: Central Nervous System • Cribriform Plate • Adenosine A1/A2A
Protocol: Prescription only: 1 spray each nostril daily (90mg NAD+). Refrigerate 2–8 °C.
Retail Price$265.00
Prescribe via PrecisionPharmananoNAD+™ Subcutaneous Vials (5mL × 200mg/mL)
Source: PrecisionPharma FL / Shady Grove ML
5mL sterile multidose vial (1,000mg total) for at-home daily subcutaneous micro-dosing. Formulated to eliminate the injection-site burning associated with raw clumped NAD+.
Delivers pure biologically active Beta-NAD+ directly into systemic circulation, avoiding gastrointestinal degradation and hepatic first-pass clearing.
Target: Systemic Tissue Sirtuins • PARP • Mitochondrial Complex I
Protocol: Prescription only: 25–100mg daily (12–50 units U-100 insulin syringe). Refrigerate 2–8 °C.
Retail Price$295.00
Prescribe via PrecisionPharmananoNAD+™ High-Concentration SC/IV (5mL × 400mg/mL)
Source: PrecisionPharma FL
High-concentration 400mg/mL formulation (2,000mg total) for therapeutic subcutaneous dosing or low-volume clinical IV infusion.
Provides rapid, high-density cellular fueling for depleted tissues, accelerating ATP regeneration and stimulating DNA repair enzymes without volume overload.
Target: Whole-Body Respiration • Complex I • PARP-1
Protocol: Prescription only: 200mg/day SC therapeutic or 250–500mg clinical IV session.
Retail Price$450.00
Clinical Provider AccessnanoNAD+™ Clinical IV Infusion Solution
Source: Molecular World Health & Compounding Partners
The clinical standard for deep cellular saturation, neuro-regeneration, and addiction/detoxification protocols, formulated with Dr. Richard Mestayer.
Rapid, controlled intravenous delivery providing immediate systemic substrate to replenish exhausted cellular refineries and activate DNA repair enzymes.
Target: Whole-Body Respiration • PARP-1 • Neuroplasticity
Protocol: Administered in clinical outpatient settings by certified IV nurses (250mg–1000mg per infusion).
Retail Price$495.00 / session
Clinical Provider AccessSS-31 (Elamipretide 100mg/mL × 5mL)
Source: PrecisionPharma FL
The premier mitochondrial inner-membrane targeted peptide (500mg total). Selectively binds to cardiolipin to stop electron leakage and restore ATP synthase efficiency.
Cardiolipin stabilizer. Reverses mitochondrial cristae fragmentation, stops reactive oxygen species (ROS) leakage, and improves proton gradient coupling.
Target: Inner Mitochondrial Membrane Cardiolipin
Protocol: Prescription only: Standard 10mg/day SC (10 units U-100). Pre-reconstituted 90-day BUD.
Retail Price$895.00
Inquire via Physician PortalMOTS-c (Mitochondrial-Derived Peptide 20mg/mL × 5mL)
Source: PrecisionPharma FL
Mitochondrial-encoded peptide (100mg total) that acts as an exercise-mimetic and master quality control signal, tagging damaged organelles for autophagic clearance.
Promotes mitochondrial fission/fusion balance and mitophagy, clearing dysfunctional organelles so healthy mitochondria can proliferate via biogenesis.
Target: AMPK Activation • Mitophagy Receptors • Glucose Disposal
Protocol: Prescription only: Microdose 1–3mg/day or Standard 5mg 2–3×/week SC. Pre-reconstituted.
Retail Price$750.00
Inquire via Physician PortalBPC-157 Solution (10mg/mL × 5mL)
Source: PrecisionPharma FL
Pentadecapeptide composed of 15 amino acids (50mg total) that accelerates structural tissue healing, protects the mucosal gut-mitochondrial axis, and modulates systemic inflammation.
Upregulates growth hormone receptors, stimulates VEGF angiogenesis, and protects endothelial and mucosal integrity from oxidative breakdown.
Target: Endothelial Cells • Gut Mucosa • Tendons & Ligaments
Protocol: Prescription only: 10 units (1mg) daily SC; 5 units (500mcg) starting. Refrigerate 2–8 °C.
Retail Price$295.00
Inquire via Physician PortalBPC-157 / TB-500 Combo Solution (5mg/5mg per mL × 5mL)
Source: PrecisionPharma FL
Synergistic recovery formulation (25mg BPC-157 + 25mg TB-500 total) combining mucosal and tendon repair with deep actin cytoskeleton remodeling.
Combines BPC-157 angiogenesis and nitric oxide modulation with TB-500 (Thymosin β4) actin sequestration to accelerate multi-system tissue recovery.
Target: Actin Filaments • Growth Factor Signaling • Connective Tissue
Protocol: Prescription only: 10 units (0.5mg each) daily SC. Pre-reconstituted 90-day BUD.
Retail Price$295.00
Inquire via Physician PortalSelank (Heptapeptide)
Source: Compounding Pharmacy Partner
Synthetic regulatory peptide selective for GABA-A receptor subtype α1. Provides profound neuro-calming without binding the α2 addictive subunit.
Modulates dopamine and serotonin metabolism while elevating BDNF in hippocampus. Used as a safe alternative to benzodiazepines without tolerance.
Target: GABA-A α1 Subunit • BDNF Expression
Protocol: Subcutaneous or intranasal delivery as directed by physician for anxiety and emotional stabilization.
Retail Price$195.00
Inquire via Physician PortalUrolithin A Softgels (500mg)
Source: Timeline / Mitopure Partner
High-potency 500mg softgels delivering pure Urolithin A (Mitopure / Timeline). The gold-standard postbiotic for triggering cellular mitochondrial recycling.
Directly activates the recycling of worn-out, dysfunctional mitochondria, complementing Dr. LeBon's mitochondrial quality control protocol.
Target: Parkin-Dependent Mitophagy • Muscle Recovery
Protocol: 2 softgels daily (500mg–1000mg) with morning meal.
Retail Price$125.00
Shop Softgels (Timeline / Affiliate)Urolithin A Bio-Gummies (Berry / Pomegranate)
Source: Timeline / Mitopure Partner
Delicious bio-active gummies delivering pure Urolithin A for individuals who prefer chewable formats. Clinical-grade mitophagy stimulation.
Triggers mitochondrial autophagy, clearing damaged organelles so fresh biogenesis can proceed without pill fatigue.
Target: Mitochondrial Renewal • Cellular Cleanliness
Protocol: 2 gummies daily with breakfast.
Retail Price$79.00
Shop Gummies (Timeline / Affiliate)CoQ10 Ubiquinol (Mitochondrial Electron Shuttle)
Source: Life Extension / Qualified Partner
The active, reduced form of Coenzyme Q10. Accepts electrons transferred by NADH at Complex I and shuttles them to Complex III in the respiratory chain.
Prevents electron backlog at the inner mitochondrial membrane, ensuring the hydrides delivered by NAD+ are seamlessly translated into the proton gradient.
Target: Mitochondrial Inner Membrane Respiratory Chain
Protocol: 100mg–200mg daily with dietary fat.
Retail Price$68.00
Shop Qualified Partner (Life Extension)Hydride-Loaded Glutathione Matrix (NAC + Reduced GSH)
Source: Life Extension / Qualified Partner
Formulated specifically to support the NAD-Glutathione pathway. Supplies cysteine building blocks and reduced glutathione alongside NADPH cofactors.
Provides the substrate for glutathione peroxidase, neutralizing free radicals produced during electron transport while NAD+ maintains the loaded hydride charge.
Target: Glutathione Reductase • Cellular Redox Homeostasis
Protocol: 500mg daily on an empty stomach.
Retail Price$89.00
Shop Qualified Partner (Life Extension)PQQ (Pyrroloquinoline Quinone)
Source: Life Extension / Qualified Partner
Potent polyphenol that stimulates CREB phosphorylation and PGC-1α expression, prompting cells to synthesize fresh, new mitochondria.
Works in tandem with MOTS-c: while MOTS-c removes damaged organelles, PQQ signals the cell nucleus to replicate new mitochondrial factories.
Target: PGC-1α • Mitochondrial DNA Transcription (TFAM)
Protocol: 20mg daily with breakfast.
Retail Price$54.00
Shop Qualified Partner (Life Extension)Affiliate & Prescribing Transparency
The Human Energy Center partners with select top-tier longevity and cellular supplement manufacturers (such as Life Extension, Timeline, and verified peptide compounders) that meet Dr. LeBon's stringent pharmacokinetic standards for rebuilding the NAD+ and mitochondrial respiratory cycle. Some product links may generate affiliate commissions that support our non-profit educational and scientific research initiatives.
Prescription items (including SubQ nanoNAD+, Selank, SS-31, and MOTS-c) are compounded medications dispensed solely by licensed 503A pharmacies (PrecisionPharma FL, Shady Grove Pharmacy ML) pursuant to a valid medical order from a licensed physician.